Lung Epithelial Cell Prep

Epithelial cell apoptosis and lung remodeling.

Lung epithelium is the primary site of lung damage in various lung diseases. Epithelial cell apoptosis has been considered to be initial event in various lung diseases. Apoptosis signaling is classically composed of two principle pathways. One is a direct pathway from death receptor ligation to caspase cascade activation and cell death. The other pathway triggered by stresses such as drugs, rad...

Epithelial cell and lung cancer: introduction.

Although cigarette smoking is considered the main risk factor for lung cancer, others, such as chronic inflammation and oxidative stress, have been identified. Chronic inflammation and oxidative stress also play a crucial role in chronic lung diseases such as COPD and IPF. Furthermore, post-transplant immunosuppressive treatment is often considered a risk factor for lung cancer. Recently, new d...

substance p potentiates tgf-1 production in lung epithelial cell lines

transforming growth factor-beta (tgf-β) is one of the most important cytokines implicated in growth, differentiation, repair and also the pathogenesis of the lung fibrosis by its stimulatory effect on extracellular matrix deposition. pulmonary epithelial cells are considered as a source of tgf-β in lung. substance p (sp), as a neuroimmunomodulator has elevated levels in inflamed airways and alt...

To prep or not to prep.

Diversity of Epithelial Stem Cell Types in Adult Lung

Lung is a complex organ lined with epithelial cells. In order to maintain its homeostasis and normal functions following injuries caused by varied extraneous and intraneous insults, such as inhaled environmental pollutants and overwhelming inflammatory responses, the respiratory epithelium normally undergoes regenerations by the proliferation and differentiation of region-specific epithelial st...